Author's response to reviews Title: Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women- A randomized control trial Authors:

نویسندگان

  • Ali A Moazzami
  • Isabel Bondia-Pons
  • Kati Hanhineva
  • Katri Juntunen
  • Nadja Antl
  • Kaisa Poutanen
  • Hannu Mykkänen
  • Ali Moazzami
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Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women- a randomized control trial

BACKGROUND Epidemiological studies have consistently shown that whole grain (WG) cereals can protect against the development of chronic diseases, but the underlying mechanism is not fully understood. Among WG products, WG rye is considered even more potent because of its unique discrepancy in postprandial insulin and glucose responses known as the rye factor. In this study, an NMR-based metabol...

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Metabolomics reveals differences in postprandial responses to breads and fasting metabolic characteristics associated with postprandial insulin demand in postmenopausal women.

Changes in serum metabolic profile after the intake of different food products (e.g., bread) can provide insight into their interaction with human metabolism. Postprandial metabolic responses were compared after the intake of refined wheat (RWB), whole-meal rye (WRB), and refined rye (RRB) breads. In addition, associations between the metabolic profile in fasting serum and the postprandial conc...

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Background: Metabolic syndrome is a disorder associated with obesity. Compared with men, postmenopausal women are at higher risk of being affected by this chronic disease. This study aimed to determine the effect of self-care education program on anthropometric indicators in postmenopausal women with metabolic syndrome. Methods: A cluster randomized controlled trial was performed on 120 postme...

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تاریخ انتشار 2012